Lupus Nephritis is resulted from systemic lupus erythematosus (SLE). If uncontrolled effectively, Lupus Nephritis may aggravate into kidney failure. If you are just diagnosed with this disease, some basic information can guide you to manage your problem correctly.
1. The causes of Lupus Nephritis
As the above mentioned, Lupus Nephritis is due to SLE which has a close link with inherited disorder, hormone, environment, infections, drugs, and autoimmune disorder. These factors disturb the body together, resulting in Lupus Nephritis. Besides, some kidney experts find that the onset of Lupus Nephritis is caused by several factors.
- Immune complexes build up in kidneys
- Situ immune complexes form
- Local complement activation
- The direct effect of antibodies
- Immune reactions induced by T cells.
2. The typical symptoms of Lupus Nephritis
If patients have Lupus Nephritis, they may have a lot of clinical manifestations such as proteinuria, hematuria, swelling, high blood pressure, joint pain, butterfly rash, and so on. All of these remind patients to take effective treatments to manage their problems immediately.
3. The conservative treatment for Lupus Nephritis
In clinic, doctors always use steroids and immunosuppressants to treat patients’ Lupus Nephritis, because these medicines have a quick and obvious effect on reducing protein leakage and managing inflammatory reactions within kidneys. However, these medicines may cause a series of side effects easily.
4. Alternative therapies for patients with Lupus Nephritis
If steroids and immunosuppressants fail to work, patients may be suggested to accept plasma exchange or Immunotherapy. These two therapies focus on removing immune complexes and protect kidneys from further damage. Besides, Immunotherapy can also help repair damaged kidney cells and rebuild kidney filtering structure.
These are some basic information about Lupus Nephritis. Any other question about this disease? Just leave it in the form below.