Purpura Nephritis, also called HSPN, is kidney disease caused by systemic disorder. Characterized by skin purpura, joint pain, stomach pain, hematuria, and proteinuria, this disease should be treated timely and actively. Today, we are here to introduce some important points to treat Purpura Nephritis.
The pathogenic changes of Purpura Nephritis
It is one hypersensitivity vasculitis disease with main membranous cells’ damage. The pathogenic changes is systemic vasculitis, the damage degree from inflammatory cells to necrotic cells, proliferation of glomerular mesangial cells, and the formation of crescent.
The triggers of Purpura Nephritis
Here, we need to remind these patients that they should emphasize not only exogenous allergens such as infections, foods and medicine but also endogenous allergens such as metabolic products, infected bacteria products, and so on. If not removed timely, these harmful substances will cause purpura nephritis to relapse again and again.
The difficulty on treating Purpura Nephritis
Because the body’s clearance ability for large molecular immune complexes declines, patients’ medical condition aggravates gradually. However, the conventional medicines can only inhibit the activity of these immune complexes rather than removing them. This is why this kidney disease can’t be treated easily.
The key of Purpura Nephritis treatment
The first step of the whole treatment is to eliminate the pathogenic factors thoroughly. Immunotherapy is one therapy that can eliminate immune complexes effectively. Besides, some medicines that can help expand blood vessels, fight against inflammatory reactions and coagulation, and repair damaged vascular intima are needed. With the help of these remedies, patients can find their health condition becomes better and better.
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